The Buffalo Bills are about to play the Los Angeles Rams at SoFi Stadium to kick off the 2022 NFL regular season.

Many experts think this could be a preview of the Super Bowl in February, which will take place in Arizona.

It's a compelling matchup of two teams who love to play up-tempo and in the Bills case, love to pass the ball as often as possible.

Bills defensive coordinator Leslie Frazier will have his hands full with the likes of quarterback Matthew Stafford and wide receivers Cooper Kupp and Allen Robinson. Tight end Tyler Higbee and running backs Cam Akers and Darrell Henderson.

The strongest part of the Bills defense since Frazier and head coach Sean McDermott took over in Buffalo has been the stellar secondary.

In fact, the Bills have been so good against the pass that believe it or not, they did not give up a single catch in a go/fly route ALL of last season, according to Football Outsiders...

They were the only defense to accomplish that in 2021.

For those who don't know, go/fly routes are basically just straight ahead, long routes that attack a defense down the field. The fact the Bills didn't give up a single completion in those routes last season shows 1) how good they're personnel is and 2) how their base defense factors in to why they play the pass so well.

The Bills have Micah Hyde and Jordan Poyer on the field 100 percent of the time and typically have nickel corner Taron Johnson on the field, instead of a third linebacker. They only have two starting linebackers in their system -- Matt Milano and Tremaine Edmunds.

The Bills will not have Tre'Davious White tonight and for at least the next three games, so Dane Jackson will have to step up, as will rookies Kaiir Elam and Christian Benford.

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